Lots of helpful information and source materials to ponder here. Thank you. Also, 'Threshold Theory', which makes perfect sense, could potentially be a good bridge term for getting some of those Germ Theorists and Terrain Theorists to talk to one another some day. Maybe.
Yes I already subscribe to Unglossed. I really enjoy his work. I also don’t completely deny the existence of “viruses.” From dissenting views I’ve read, they exist in that strands of RNA exist, but the impact they have of living systems and the mechanisms by which they have the theorized impacts are quite as clearly understood or even proven to the extent the proponents of viral theory would have us believe.
Great article. The foundation of my Functional Nutrition studies is the microbiome, which I began learning about in 2013 at an Integrative Physician’s Symposium. But the ancient sciences like Ayurveda and Traditional Chinese Medicine, were emphasizing gut and digestive health thousands of years ago!
My former husband has Parkinson’s disease. He’s had gut issues since we met 33 years ago. I helped him by changing his diet while we were married, removing dairy and other inflammatory foods plus alcohol, which is known to contribute to leaky gut.
Slightly off-topic but do you think treatment with the "lean" type bacteria could support people who need to lose weight? You could make a fortune out of that?!!
Thank you, Gary. I think this is very pertinent and timely information. Arriving at it from a different direction, I have long believed in the connection between the gut microbiome and chronic stress.
Thanks for the shout out Gary! The bottom line for me is that it's all related. We can't treat any one thing in our body without it having an effect on everything else, even if marginally. And when the system collapses, you need a full system reset.
Gut health is such an interesting one to me because so many people (unsurprisingly) have bought into the idea of dumping billions of "good" bacteria into our guts in the form of supplements and food additives. But I would say that's largely just so people can sell stuff to consumers. The better question to ask is why did the natural good bacteria in your gut go away in the first place? If the gut environment is inhospitable, then dumping more good bacteria in there doesn't solve the problem. It's sort of like having a gas leak in a building that kills everyone and trying to solve the issue by sending in more people. They are going to die too until you fix the gas leak itself...
Jan 12, 2023·edited Jan 12, 2023Liked by Gary Sharpe
Thank you Gary for this wonderful post!
I've lived with severe gastroparesis for most of my life. The information you shared here is very similar to the background and treatment protocol for what I guess we can call related diseases (since many seem to have a common root). I believe that vagus nerve damage is the common thread in my case, but then I would have to explain similar symptomology in relatives. There appears to be a possible disbiosis mechanism involved where the condition is passed on and the chronic damage repeats.
As an optimist (when I'm not pushing doom and gloom) I believe some of the damage can be reversed by regular fasting and use of fermented foods. The main task (as you mentioned) is to identify inflammatory inputs and reduce them. Inflammation has its place, but chronic inflammation is bad news.
It appears we could all do with an infusion of healthy microbiome material (which appears to correct hereditary traits), but I'm not keen on the transferred poop solution!
Anyway, I hope it goes well for you and all others in this struggle.
Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTPAuthor links open overlay panelYaoyuPuLijiaChangYougeParkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder. Epidemiological studies suggest that the exposure of the herbicide glyphosate may influence the development of PD in humans. In this study, we examined whether the exposure of glyphosate can affect the reduction of dopamine transporter (DAT) in the striatum and tyrosine hydroxylase (TH) in the substantial nigra (SNr) of mouse brain after repeated administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Repeated injections of MPTP (10 mg/kg × 3, 2-h interval) significantly decreased the density of DAT-immunoreactivity in the striatum and the number of TH-immunoreactivity in the SNr. Glyphosate exposure for 14 days significantly potentiated MPTP-induced dopaminergic neurotoxicity in the striatum and SNr of mouse brain. This study suggests that glyphosate exposure might exacerbate MPTP-induced dopaminergic neurotoxicity in the striatum and SNr of adult mice. It is likely that exposure of glyphosate may be an environmental risk factor for PD since glyphosate has been used widely in the world.
We need more people like you in the medical field!!! I love the teams at hospital who woek together to discern health and collaboration. I was just wriging to a freind on this fery subject on the body had how this kind of collaboration is necessary and ego avoided for that very needy. this is why you are so helpful in puting gogether you program in healing and spead what you learn. No egos involved, just pure Science of healing.
Another great article, Gary. Totally with you about the "threshold" idea. Stress itself is not the problem. It's the balance between stress and resilience in my experience.
Lots of helpful information and source materials to ponder here. Thank you. Also, 'Threshold Theory', which makes perfect sense, could potentially be a good bridge term for getting some of those Germ Theorists and Terrain Theorists to talk to one another some day. Maybe.
Yes I already subscribe to Unglossed. I really enjoy his work. I also don’t completely deny the existence of “viruses.” From dissenting views I’ve read, they exist in that strands of RNA exist, but the impact they have of living systems and the mechanisms by which they have the theorized impacts are quite as clearly understood or even proven to the extent the proponents of viral theory would have us believe.
Thanks so much!
Great article. The foundation of my Functional Nutrition studies is the microbiome, which I began learning about in 2013 at an Integrative Physician’s Symposium. But the ancient sciences like Ayurveda and Traditional Chinese Medicine, were emphasizing gut and digestive health thousands of years ago!
My former husband has Parkinson’s disease. He’s had gut issues since we met 33 years ago. I helped him by changing his diet while we were married, removing dairy and other inflammatory foods plus alcohol, which is known to contribute to leaky gut.
Slightly off-topic but do you think treatment with the "lean" type bacteria could support people who need to lose weight? You could make a fortune out of that?!!
Thank you, Gary. I think this is very pertinent and timely information. Arriving at it from a different direction, I have long believed in the connection between the gut microbiome and chronic stress.
Fascinating and helpful information once again. I love how you connect such relevant information. Thank you, Gary.
Thanks for the shout out Gary! The bottom line for me is that it's all related. We can't treat any one thing in our body without it having an effect on everything else, even if marginally. And when the system collapses, you need a full system reset.
Gut health is such an interesting one to me because so many people (unsurprisingly) have bought into the idea of dumping billions of "good" bacteria into our guts in the form of supplements and food additives. But I would say that's largely just so people can sell stuff to consumers. The better question to ask is why did the natural good bacteria in your gut go away in the first place? If the gut environment is inhospitable, then dumping more good bacteria in there doesn't solve the problem. It's sort of like having a gas leak in a building that kills everyone and trying to solve the issue by sending in more people. They are going to die too until you fix the gas leak itself...
Thank you Gary for this wonderful post!
I've lived with severe gastroparesis for most of my life. The information you shared here is very similar to the background and treatment protocol for what I guess we can call related diseases (since many seem to have a common root). I believe that vagus nerve damage is the common thread in my case, but then I would have to explain similar symptomology in relatives. There appears to be a possible disbiosis mechanism involved where the condition is passed on and the chronic damage repeats.
As an optimist (when I'm not pushing doom and gloom) I believe some of the damage can be reversed by regular fasting and use of fermented foods. The main task (as you mentioned) is to identify inflammatory inputs and reduce them. Inflammation has its place, but chronic inflammation is bad news.
It appears we could all do with an infusion of healthy microbiome material (which appears to correct hereditary traits), but I'm not keen on the transferred poop solution!
Anyway, I hope it goes well for you and all others in this struggle.
Thank you!
Of huge interest to me.
Eschewing GMO foods is critical:
RESEARCH ARTICLE ON GMOs and PARKINSON'S
https://www.sciencedirect.com/science/article/abs/pii/S0304394020303025esearch article
Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTPAuthor links open overlay panelYaoyuPuLijiaChangYougeParkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder. Epidemiological studies suggest that the exposure of the herbicide glyphosate may influence the development of PD in humans. In this study, we examined whether the exposure of glyphosate can affect the reduction of dopamine transporter (DAT) in the striatum and tyrosine hydroxylase (TH) in the substantial nigra (SNr) of mouse brain after repeated administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Repeated injections of MPTP (10 mg/kg × 3, 2-h interval) significantly decreased the density of DAT-immunoreactivity in the striatum and the number of TH-immunoreactivity in the SNr. Glyphosate exposure for 14 days significantly potentiated MPTP-induced dopaminergic neurotoxicity in the striatum and SNr of mouse brain. This study suggests that glyphosate exposure might exacerbate MPTP-induced dopaminergic neurotoxicity in the striatum and SNr of adult mice. It is likely that exposure of glyphosate may be an environmental risk factor for PD since glyphosate has been used widely in the world.
We need more people like you in the medical field!!! I love the teams at hospital who woek together to discern health and collaboration. I was just wriging to a freind on this fery subject on the body had how this kind of collaboration is necessary and ego avoided for that very needy. this is why you are so helpful in puting gogether you program in healing and spead what you learn. No egos involved, just pure Science of healing.
Another great article, Gary. Totally with you about the "threshold" idea. Stress itself is not the problem. It's the balance between stress and resilience in my experience.
Threshold theory sounds like a version of complexity theory. Within it there all sorts of checks and balances that modulate system interactions.
Absolutely fascinating. Where would one go to have gut microbiome characterized?